Seung Gu Park


Seung Gu Park, Ph.D


Research Interests 



08/2009 ~ 02/2014    Kangwon National University, South Korea
Ph.D. in Department of Biotechnology

Thesis: Multidimensional integratomic approach in understanding genome evolution, expression and function
Advisor: Prof. Sun Shim Choi

08/2007 ~ 08/2009    Kangwon National University, South Korea
Master of Science in Department of Biotechnology

Thesis: Positive selection signature in the TLR7 family
Advisor: Prof. Sun Shim Choi

03/2001 ~ 08/2007    Kangwon National University, South Korea
Bachelor of Science in Department of Medical Biotechnology

Postdoctoral Fellowship

04/2014 ~ 04/2016     Postdoctoral Research Associate, Hannelhalli Lab, University of Maryland Institute for Advanced Computer Studies (UMIACS), University of Maryland, College Park
Mentor: Prof. Sridhar Hannenhalli

05/2016 ~    Postdoctoral Research Associate, Korean Genomics Industrialization and Commercialization Center (KOGIC), Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea.
Mentor: Prof. Jong Bhak


Massive Data Merging Compression Apparatus and Method based on Gene Sequence using Binary Notation, Seung Gu Park and Sun Shim Choi, Korea Patent
Display Apparatus and Method for DNA Sequence and Comments Information, Seung Gu Park and Sun Shim Cho, Korea Patent
Antibody Structure Sequence Numbering Apparatus and Method based on Next Generation Sequencing Data, Seung Gu Park and Sun Shim Choi, Korea Patent


Kim, H.M., Weber, J.A., Lee, N., Park, S.G., Cho, Y.S., Bhak, Y., Lee, N., Jeon, Y., Jeon, S., Luria, V. and Karger, A., 2018. The jellyfish genome sheds light on the early evolution of active predation. bioRxiv, p.449082.
Park, S.G., Luria, V., Weber, J.A., Jeon, S., Kim, H.M., Jeon, Y., Bhak, Y., Jun, J., Kim, S.W., Hong, W.H. and Lee, S., 2018. The whale shark genome reveals how genomic and physiological properties scale with body size. bioRxiv, p.443036.
Shin, E.S., Park, S.G., Saleh, A., Lam, Y.Y., Bhak, J., Jung, F., Morita, S. and Brachmann, J., 2018. Magnetocardiography scoring system to predict the presence of obstructive coronary artery disease. Clinical Hemorheology and Microcirculation, (Preprint), pp.1-9.
Lee, J.S., Das, A., Jerby-Arnon, L., Arafeh, R., Auslander, N., Davidson, M., McGarry, L., James, D., Amzallag, A., Park, S.G. and Cheng, K., 2018. Harnessing synthetic lethality to predict the response to cancer treatment. Nature communications, 9(1), p.2546.
Nair, N.U., Das, A., Amit, U., Robinson, W., Park, S.G., Basu, M., Lugo, A., Leor, J., Ruppin, E. and Hannenhalli, S., 2018. Putative functional genes in idiopathic dilated cardiomyopathy. Scientific reports, 8(1), p.66.
Sahu, A., Lee, J.S., Zhang, G., Wang, Z., Tian, T., Moll, T., Kasumova, G., Miao, B., Wei, Z., Nair, N.U. and Ponomarova, O., 2018. Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy. bioRxiv, p.284240.
Kim, S., Park, I., Park, S.G., Cho, S., Kim, J.H., Ipper, N.S., Choi, S.S., Lee, E.S. and Hong, H.J., 2017. Generation, Diversity Determination, and Application to Antibody Selection of a Human Naïve Fab Library. Molecules and Cells, 40(9), p.655.
Malin, J., Ezer, D., Ma, X., Mount, S., Karathia, H., Park, S.G., Adryan, B. and Hannenhalli, S., 2015. Crowdsourcing: Spatial clustering of low-affinity binding sites amplifies in vivo transcription factor occupancy. bioRxiv, p.024398.
Park, S.G. and Hannenhalli, S., 2015. First intron length in mammals is associated with 5′ exon skipping rate. bioRxiv, p.024463.
Park, S.G., Hannenhalli, S. and Choi, S.S., 2014. Conservation in first introns is positively associated with the number of exons within genes and the presence of regulatory epigenetic signals. BMC genomics, 15(1), p.526.
Cho, H., Han, S., Choe, J., Park, S.G., Choi, S.S. and Kim, Y.K., 2012. SMG5–PNRC2 is functionally dominant compared with SMG5–SMG7 in mammalian nonsense-mediated mRNA decay. Nucleic acids research, 41(2), pp.1319-1328.
Yang, H., Ko, H.J., Yang, J.Y., Kim, J.J., Seo, S.U., Park, S.G., Choi, S.S., Seong, J.K. and Kweon, M.N., 2012. Interleukin-1 promotes coagulation, which is necessary for protective immunity in the lung against Streptococcus pneumoniae infection. The Journal of infectious diseases, 207(1), pp.50-60.
Cho, H., Kim, K.M., Han, S., Choe, J., Park, S.G., Choi, S.S. and Kim, Y.K., 2012. Staufen1-mediated mRNA decay functions in adipogenesis. Molecular cell, 46(4), pp.495-506.
Mok, Y.J., Park, S.G. and Choi, S.S., 2012. Comparative analysis of the structural and expressional parameters of microRNA target genes. Gene, 497(1), pp.103-109.
Park, S.G., Kwon, K.H. and Choi, S.S., 2012. Analysis of putative miRNA function using a novel approach, GAPPS-miRTarGE. Genes & Genomics, 34(2), pp.205-216.
Park, S.G. and Choi, S.S., 2010. Expression breadth and expression abundance behave differently in correlations with evolutionary rates. BMC evolutionary biology, 10(1), p.241.
Park, S.G., Park, D., Jung, Y.J., Chung, E. and Choi, S.S., 2010. Positive selection signatures in the TLR7 family. Genes & Genomics, 32(2), pp.143-150.
Park, D., Park, J., Park, S.G., Park, T. and Choi, S.S., 2008. Analysis of human disease genes in the context of gene essentiality. Genomics, 92(6), pp.414-418.